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Emerging Therapeutic Advancements for the Multimodal Treatment of Postoperative Ileus

August 2007
This program is supported by an unrestricted educational grant from Adolor Corporation and GlaxoSmithKline.
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A better understanding of the pathophysiology of postoperative ileus (POI) and the development of new treatment modalities will improve management, shorten duration of POI, reduce hospital stay, and decrease health care costs.

On completion of this activity, participants should be better able to:

  • Describe the clinical and economic impact of postoperative ileus (POI) on patient outcomes following major abdominal surgery.
  • Discuss the latest nonpharmacologic and pharmacologic approaches to mitigating POI, including minimally invasive surgical techniques, early oral feeding, early ambulation, and opioidsparing anesthesia/analgesia.
  • Develop and implement a multimodal postoperative care program to accelerate recovery and reduce length of hospital stay following major abdominal surgery.
  • Discuss the latest trials of pharmacologic agents currently in development to hasten postoperative bowel recovery, including prokinetic agents, gastrointestinal hormone analogues, and peripheral ?-opioid receptor antagonists.

The faculty members for this program are:

Richard P. Billingham, MD
Clinical Professor, Department of Surgery
University of Washington
Northwest Colon and Rectal Clinic
Seattle, Washington

Benjamin Person, MD
Advanced Clinical Research Fellow
Department of Colorectal Surgery
Cleveland Clinic Florida
Weston, Florida

Anthony Senagore, MD, MS, MBA
Professor of Surgery
Michigan State University
Vice President, Research and Education
Spectrum Health
Grand Rapids, Michigan

Steven D. Wexner, MD, FACS, FRCS, FRCS (Ed)
Chief of Staff, Cleveland Clinic Hospital
Chair, Department of Colorectal Surgery
Cleveland Clinic Florida
Weston, Florida

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